Passiflora, 60's

Passiflora — passionflower (Passiflora incarnata) supplement studied for alcohol withdrawal support (benzoflavone reduced withdrawal effects and anxiety in chronic and acute administration, chronic use showing better preventive effects), opioid withdrawal support (double-blind RCT of clonidine + passiflora extract vs clonidine + placebo in outpatient detoxification of 65 opiate addicts; passiflora + clonidine superior in management of mental symptoms), smoking cessation, helping process stressful situations and maintain emotional well-being, potential adjuvant in depression especially if associated with anxiety (long-term use correlated with reduced stress, increased motivation and improved motor activity; memory function benefits confirmed), antioxidant and anti-inflammatory bioactive compounds (flavonoids, phenolic acids, polyphenols).